Manning may be coming off a Week 1 victory but he failed to throw a touchdown pass and threw only 175 yards against the Ravens. The Chiefs defense, led by ferocious pass rusher Justin Houston, will be looking to pressure and punish Manning into another poor performance and force Denver's first loss.
As always, the pick is against the spread and the home team is in CAPS.
CHIEFS (-3) over Broncos
Last Week: 6-9-1